The museum has three permanent exhibitions: "Nature", "Life", "History". Birds and animals of Seryshevsky district and Amur region are represented in the hall of nature. In the hall of everyday life there are various items that were brought to the territory of Seryshevsky district by immigrants. The history hall tells about the civil war on the territory of the Seryshvsky district, about the veterans of the Great Patriotic War, about the inhabitants of Seryshevo - the heroes of the Soviet Union and the Russian Federation, etc.